胡芦巴对实验性糖尿病大鼠脂代谢及肾脏抗氧化防御功能的影响

吉林大学再生医学科学研究所病理研究室，吉林 长春130021目的：探讨胡芦巴对糖尿病大鼠脂代谢及肾脏抗氧化能力的影响。方法: 用胡芦巴治疗糖尿病大鼠12周后,观察其血脂水平及肾脏的抗氧化能力。 结果:经过胡芦巴治疗的糖尿病大鼠血脂水平下降，肾脏超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）及过氧化氢酶（CAT）活性有所升高，丙二醛（MDA）水平下降。结论:胡芦巴能够调解糖尿病大鼠的脂代谢紊乱，增强肾脏的抗氧化能力。吉林大学再生医学科学研究所病理研究室，吉林 长春130021目的：探讨胡芦巴对糖尿病大鼠脂代谢及肾脏抗氧化能力的影响。方法: 用胡芦巴治疗糖尿病大鼠12周后,观察其血脂水平及肾脏的抗氧化能力。 结果:经过胡芦巴治疗的糖尿病大鼠血脂水平下降，肾脏超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）及过氧化氢酶（CAT）活性有所升高，丙二醛（MDA）水平下降。结论:胡芦巴能够调解糖尿病大鼠的脂代谢紊乱，增强肾脏的抗氧化能力。

Effects of fenugreek seeds on lipid metabolism and kidney antioxidant defense function in experimental diabetic rats

Objective To study the effects of fenugreek seeds on lipid metabolism and kidney antioxidant defense function in diabetic rats. Methods Diabetic rats were treated with fenugreek seeds for 12 weeks,the blood lipid level and kidney antioxidant function were observed. Results The level of blood lipid was reduced, the activities of superoxide dismtase(SOD),glutathion peroxidantion(GSH-Px),and catalase(CAT) were increased in diabetic rats treated with fenugreek seeds.The level of lipid peroxidantion(MDA) in diabetic rats treated with fenugreek seeds was lower than that in untreated group. Conclusion Fenugreek seeds can morderate the lipid metabolism and enhance the kidney antioxidant function in diabetic rats.