The biological role of blood vessels during endochondral bone formation |
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Authors: | Amizuka Norio Sasaki Tomoyo Maeda Takeyasu |
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Affiliation: | Division of Oral Anatomy, Department of Oral Biological Science Niigata University, Graduate School of Medical and Dental Sciences. |
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Abstract: | Endothelial cells play an important role in endochondral bone formation. In the chondro-osseous junction, endothelial cells appear to invade into cartilage by the cellular mechanism of angiogenesis evidenced by cell duplication, disappearance of basement membranes and activated migration. The endothelial cells penetrate the unmineralized transverse partition of the cartilage columns. |
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