风心病二尖瓣狭窄合并肺动脉高压的肺病理研究

目的：观察风湿性心脏病（风心病）二尖瓣狭窄肺动脉高压口才肺病理改变特点,为临床处理提供理论依据。方法：选择３７例风心病二尖瓣狭窄合并肺动脉高压的手术换瓣患者,在手术时取右肺中叶组织,结其病理改变进行定性和定量研究。以６例主动脉瓣病变、肺动脉压正常、行主动脉瓣置换术的患者为对照。结果：风心病二尖瓣狭窄合并肺动脉高压患者的肺组织结构存在着不同程度的改变。严重肺动脉高压组的肺肌型动脉中层厚度指数（ＭＴ／

Pathology of the lungs in rheumatic mitral stenosis with pulmonary hypertension

Objective: To review the pathological characteristics of the lungs in mitral stenosis with pulmonary hypertension, and provide evidence for clinical treatment. Methods: Pulmonary pathological changes in 37 patients with rheumatic mitral stenosis and secondary pulmonary hypertension received mitral valve replacement. Six patients of aortic valve disease without pulmonary hypertension received aortic valve replacement and were taken as control. The lung biopsies were obtained from the middle lobe of the right lung in operation. Pulmonary muscular arteries were studied quantitatively and qualitatively. Results: All patients with mitral stenosis showed various degrees of vascular and other associated parenchymal changes. The structural changes in the muscular arteries was graded according to the degree of MT/R. There was 81% of patients with mitral stenosis in mild to moderate degree. Conclusion: The pulmonary vascular pathological changes of patients who have rheumatic mitral stenosis with pulmonary hypertension are related to the level of preoperative pulmonary artery pressure. And in most of them the pulmonary vascular pathological changes are in mild to moderate degree.