| 雷公藤甲素药理作用研究新进展 |
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| 引用本文： | 崔进,陈晓,苏佳灿.雷公藤甲素药理作用研究新进展[J].中国中药杂志,2017,42(14):2655-2658. |
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| 作者姓名： | 崔进 陈晓 苏佳灿 |
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| 作者单位： | 第二军医大学 附属长海医院 创伤骨科, 上海 200433,第二军医大学 附属长海医院 创伤骨科, 上海 200433,第二军医大学 附属长海医院 创伤骨科, 上海 200433 |
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| 基金项目： | 国家中医药管理局中医药行业专项（2012070025-02）；2012年甘肃省中医药管理局项目（GZK-2012-21）；甘肃省科技计划基础研究创新群体项目（1606RJIA323）；中央财政引导地方科技创新平台项目（2016-A-02） |
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| 摘 要： | 雷公藤甲素是中药雷公藤的主要活性成分。目前雷公藤甲素已被用作多种疾病的治疗,包括:狼疮,肿瘤,类风湿性关节炎,肾病综合征等。雷公藤甲素的主要药理作用包括:抗炎、抗肿瘤、免疫抑制等,近期研究表明雷公藤甲素对心血管疾病及骨质疏松均有保护作用。该文以近期雷公藤甲素的研究进展为基础,对雷公藤甲素的药理作用进行综述。
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| 关 键 词： | 雷公藤甲素 药理作用 肿瘤 炎症 骨质疏松 |
| 收稿时间： | 2017/4/6 0:00:00 |
Advanced progress of main pharmacology activities of triptolide |
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| CUI Jin,CHEN Xiao and SU Jia-can.Advanced progress of main pharmacology activities of triptolide[J].China Journal of Chinese Materia Medica,2017,42(14):2655-2658. |
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| Authors: | CUI Jin CHEN Xiao and SU Jia-can |
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| Institution: | Department of Trauma Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China,Department of Trauma Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China and Department of Trauma Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Triptolide is an active component in traditional Chinese medicine Tripterygium wilfordii. Currently, triptolide has been used to treat various diseases, including lupus, cancer, rheumatoid arthritis and nephritic syndrome. Its main pharmacology efficacies include anti-inflammation, anti-tumor, and immunity suppression. Recent studies have also demonstrated triptolide''s protective effect on cardiovascular diseases and osteoporosis. This paper summarizes the pharmacological efficacy of triptolide based on the advance in studies of triptolide. |
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| Keywords: | triptolide pharmacological activity tumor inflammation osteoporosis |
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