慢性肾衰竭患者药物性脑病91例临床分析

目的 探讨引起慢性肾衰竭患者发生药物性脑病的常见抗生素种类、危险因素、临床特点、治疗及转归.方法 对发生药物性脑病的91例慢性肾衰竭患者所使用的药物种类、发病后的临床特点、治疗及转归进行分析.结果 91例慢性肾衰竭患者引起药物性脑病发生的抗生素包括:头孢他啶、头孢吡肟、头孢哌酮钠、拉氧头孢、头孢呋辛钠、加替沙星、哌拉两林.药物性脑病的发生与抗生素剂量有明显关系.结论 各种抗生素致慢性肾衰竭患者发生药物性脑病如能及早发现、及早停药及对症治疗如强化血液透析,绝大多数病人预后良好.

Clinical ananlysis of medicine-induced encephalopathy in patients with chronic renal failure

Objectives To study the common types of antibiotics result in encephalopathy in ESRD patients,its risk factors,clinical feature,treatment and prognosis.Methods The clinical data of the 91 cases of medicine-induced encephalopathy in patients with chronic renal failure were analysed.Results Seven types of antibiotics were the common types of medicine inducing encephalopathy in the 91 cases of encephalopathy in patients with ESRD.Conventional dose of these antibiotics was correlated with the occurrence of medicine-induced encephalopathy.Conclusions Better prognosis can be achieved with early diagnosis and treatment such as enhaced hemodialysis.