| 1,25-二羟维生素D3与自身免疫性疾病 |
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| 引用本文： | 邹敏书. 1,25-二羟维生素D3与自身免疫性疾病[J]. 国际儿科学杂志, 2010, 37(4): 625-627. DOI: 10.3760/cma.j.issn.1673-4408.2010.06.025 |
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| 作者姓名： | 邹敏书 |
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| 作者单位： | 广州军区武汉总医院儿科,430070; |
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| 摘 要： | 1,25-二羟维生素D3对T细胞、B细胞、巨噬细胞、树突状细胞和角化细胞等均有调节作用,并与许多自身免疫性疾病包括类风湿性关节炎、青少年糖尿病、克罗恩病、多发性硬化等密切相关.1,25-二羟维生素D3可能成为治疗自身免疫性疾病的药物之一,但最佳用药剂量及疗程尚需进一步研究.
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| 关 键 词： | 1,25-二羟维生素D3 T细胞 B细胞 自身免疫性疾病 |
1,25-Dihydroxyvitamin D3 and autoimmune diseases |
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| ZOU Min-shu. 1,25-Dihydroxyvitamin D3 and autoimmune diseases[J]. International Journal of Pediatrics, 2010, 37(4): 625-627. DOI: 10.3760/cma.j.issn.1673-4408.2010.06.025 |
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| Authors: | ZOU Min-shu |
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| Abstract: | 1,25-dihydroxyvitamin D3 plays a role in the regulation of T cells, B cells, macrophages,dendritic cells,and keratinocytes. 1,25-dihydroxyvitamin D3 is linked to many autoimmune diseases, including rheumatoid arthritis,juvenile diabetes, Crohn's disease, multiple sclerosis. It may have potential as a treatment for autoimmune diseases, however, additional research will focus on better quantify dosage and course of treatment. |
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| Keywords: | 1 25-Dihydroxyvitamin D3T cellB cellAutoimmune diseases |
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