| 胸腺基质淋巴细胞生成素在呼吸道感染中的作用 |
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| 引用本文： | 李晓庆,龚建宏. 胸腺基质淋巴细胞生成素在呼吸道感染中的作用[J]. 国际儿科学杂志, 2010, 37(4): 591-593. DOI: 10.3760/cma.j.issn.1673-4408.2010.06.014 |
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| 作者姓名： | 李晓庆 龚建宏 |
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| 作者单位： | 蚌埠医学院研究生部,233000;上海市中西医结合医院儿科,200082; |
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| 摘 要： | 胸腺基质淋巴细胞生成素(TSLP)是一个上皮细胞来源的细胞因子,对树突状细胞的极化和Th2细胞因子的产生有极其重要的影响.在T细胞受体活化和Th2细胞因子产生过程中,TSLP也直接促进T细胞增殖.研究发现,TSLP对呼吸道感染和非特异性炎症过程有广泛的免疫调节作用.
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| 关 键 词： | 胸腺基质淋巴细胞生成素 感染 非特异性炎症 呼吸道 免疫 |
Recent advances of thymic stromal lymphopoietin in respiratory tract infection |
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| LI Xiao-qing,GONG Jian-hong. Recent advances of thymic stromal lymphopoietin in respiratory tract infection[J]. International Journal of Pediatrics, 2010, 37(4): 591-593. DOI: 10.3760/cma.j.issn.1673-4408.2010.06.014 |
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| Authors: | LI Xiao-qing GONG Jian-hong |
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| Abstract: | Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine. TSLP exerts a profound influence on the polarization of dendritic cells and T helper2 cytokine production. TSLP also directly promotes T-cell proliferation in response to T-cell receptor activation and Th2 cytokine production. TSLP affects different populations of cells,indicative of the broad role of TSLP in the regulation of respiratory tract infected and inflammatory processes. |
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| Keywords: | Thymic stromal lymphopoietinInfectionInflammationRespiratory tractImmune |
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