Positron CT imaging using a high resolution PCT device (Positologica-I),11CO,13NH3, and18FDG in clinical evaluation of cerebrovascular diseases |
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| Authors: | Fumio Shishido M.D. Yukio Tateno Tsuneo Takashima Seiichi Tamachi Akira Yamaura Toshio Yamasaki |
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| Affiliation: | (1) National Institute of Radiological Sciences, Chiba, Japan;(2) Chiba University School of Medicine, Chiba, Japan;(3) Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshu-Kubota-machi, 010 Akita City, Akita, Japan |
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| Abstract: | Positron computed tomography (PCT) was performed in 3 normal volunteers and 21 patients with cerebrovascular diseases using a high resolution PCT device  Positologica-I and three tracers11CO,13NH3, and18FDG. Relatively early lesions showed various accumulation patterns, and metabolism and perfusion mismatches were clearly shown by this measurement. One type of mismatch is luxury perfusion which had a slight increase of blood volume. Another type of uncoupling is misery perfusion. Remote effects of ischemic lesions also appeared on PCT with18FDG and13NH3. From our clinical results, the PCT method with a high resolution device and radiopharmaceuticals such as11CO,13NH3, and18FDG is very useful in the assessment of cerebrovascular diseases and in defining circulatory dysfunction in man. |
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