Helicobacter pylori heat shock protein 60 antibodies are associated with gastric cancer |
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| Authors: | Aki Tanaka Tomoari Kamada Kenji Yokota Akiko Shiotani Jiro Hata Keiji Oguma Ken Haruma |
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| Affiliation: | 1. Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan;2. Department of Bacteriology, Okayama University Medical School, Okayama, Japan;3. Divison of Endoscopy and Ultrasonography, Kawasaki Medical School, Kuashiki, Okayama, Japan |
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| Abstract: | Helicobacter pylori infection causes atrophic gastritis, peptic ulcer, and gastric cancer. The host immune response plays an important role in the pathogenesis of H. pylori-related diseases. Heat shock proteins are antigens involved in various diseases. This study evaluated seropositivity for antibodies to H. pylori heat shock protein 60 in patients with gastric cancer. |
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| Keywords: | H. pylori, Helicobacter pylori MALT, gastric mucosa-associated lymphoid tissue SOD, superoxide dismutase hsp's, Heat shock proteins RE, reflux esophagitis ELISA, enzyme-linked immunosorbent assay PBS, phosphate-buffered saline CagA, cytotoxin-associated gene A |
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