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| 乳腺癌超声征象与ER、PR、C-erbB-2表达的相关性研究 | |
| 引用本文： | 曾红艳,曹永政,彭格红,陶文鸿,唐文台.乳腺癌超声征象与ER、PR、C-erbB-2表达的相关性研究[J].中国医学影像技术,2007,23(12):1827-1830. |
| 作者姓名： | 曾红艳 曹永政 彭格红 陶文鸿 唐文台 |
| 作者单位： | 1. 遵义医学院附属医院超声科,贵州,遵义,563003;广州市花都区人民医院超声科,广东,广州,510800 2. 遵义医学院附属医院超声科,贵州,遵义,563003 3. 遵义医学院附属医院病理科,广东,广州,51080 |
| 摘 要： | 目的初步探讨乳腺癌超声特征与免疫组织化学因子ER、PR及C-erbB-2表达的相关性,为临床乳腺癌术前辅助治疗及预后判断提供更多的信息和科学依据。方法44例乳腺癌均经病理组织学证实,且所有病例在治疗前均行乳腺超声检查,术后测定ER、PR、C-erbB-2的表达。分析乳腺癌的超声表现与三因子表达的相关性。结果①乳腺癌三因子的表达与肿块直径无关(P>0.05)。②有毛刺征的肿块比边缘光整的肿块有更高的ER阳性表达(P<0.01)。③腋窝淋巴结转移组中C-erBb-2阳性表达率高(P<0.05),ER阳性表达率低(P<0.01)。④彩色多普勒显示血流越丰富,C-erBb-2阳性表达率越高(P<0.01)。结论乳腺癌的超声表现与免疫组织化学因子之间有一定的相关性。有毛刺征及无淋巴结转移的乳腺癌有更高的ER阳性表达率,更适合内分泌治疗;血流丰富、有淋巴结转移者C-erBb-2阳性表达率高,预示肿块恶性程度高,预后不良。 |
| 关 键 词： | 乳腺肿瘤 超声检查 多普勒 彩色 雌激素受体(ER) 孕激素受体(PR) |
| 文章编号： | 1003-3289（2007）12-1827-04 |
| 收稿时间： | 2007-09-13 |
| 修稿时间： | 2007-10-17 |
Correlation of color Doppler ultrasound morphologic features with the expression of ER, PR and C-erbB-2 in breast carcinoma |
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| ZENG Hong-yan,CAO Yong-zheng,PENG Ge-hong,TAO Wen-hong and TANG Wen-tai.Correlation of color Doppler ultrasound morphologic features with the expression of ER, PR and C-erbB-2 in breast carcinoma[J].Chinese Journal of Medical Imaging Technology,2007,23(12):1827-1830. | |
| Authors: | ZENG Hong-yan CAO Yong-zheng PENG Ge-hong TAO Wen-hong and TANG Wen-tai |
| Institution: | Department of Ultrasound, 3.Department of Pathology, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, China;;Department of Ultrasound, 3.Department of Pathology, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, China;Department of Ultrasound, 3.Department of Pathology, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, China;Department of Ultrasound, 3.Department of Pathology, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, China;Department of Ultrasound, 3.Department of Pathology, Affiliated Hospital of Zunyi Medical College, Zunyi 563003, China |
| Abstract: | |
| Keywords: | C-erB-2 |
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