血脂,脂蛋白,载脂蛋白与脑卒中

对９０例脑梗塞和９０例脑溢血患者以及１０７例对照者的血脂，脂蛋白和载脂蛋白水平进行测定。结果发现脑梗塞病人ＴＣ，ＬＤＬ－Ｃ，Ｌｐ（ａ）水平较对照组高，而ＨＤＬ－Ｃ及ＡｐｏＡＩ较对照组低。脑溢血病人ＴＣ，ＬＤＬ－Ｃ及Ｌｐ（ａ）水平较对照组显著降低。

Serum lipids, lipoprotein and stroke]

The serum levels of lipids and lipoproteins were measured in 180 consecutive patients with acute stroke(90 hemorrhagic stroke, 90 ischemic stroke) and 107 age- and sex-matched controls. As compared with the control group, hemorrhagic group had lower levels of total cholesterol(TC) (P < 0.05), low density lipoprotein-cholesterol(LDL-C) (P < 0.01) and Lp(a) (P < 0.05) while the ischemic group had higher serum TC(P < 0.05), LDL-C(P < 0.01), Lp(a) (P < 0.01) and lower high density lipoprotein-cholesterol(HDL-C) (P < 0.05) and ApoAI(P < 0.01). Multiple factor logistic regression showed that cigarette smoking, hypertension and family history of stroke were the common risk factors for both hemorrhagic and ischemic stroke, and that lowered TC and elevated LP(a) levels were independent risk factors for hemorrhagic stroke and ischemic stroke respectively.