| 原发性肾病综合征患者抗心磷脂抗体的研究 |
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| 引用本文： | 游运辉,吴彩玲.原发性肾病综合征患者抗心磷脂抗体的研究[J].湖南医科大学学报,1999,24(2):147-149. |
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| 作者姓名： | 游运辉 吴彩玲 |
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| 摘 要： | 检测６８例原发性肾病综合征和３０例正常人抗心磷脂抗体。结果示：Ａｃｌ抗体阳性率分别为３２．３５％和３．３３％，阳性组的高凝状态及肾小球损伤比阴性组病人更为明显，且治疗的敏感性也显著降低。
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| 关 键 词： | 肾病综合征 发病机制 抗心磷脂抗体 |
Study on anticardiolipin antibody in the patients with primary nephrotic syndrome] |
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| Y You,C Wu.Study on anticardiolipin antibody in the patients with primary nephrotic syndrome][J].Bulletin of Hunan Medical University,1999,24(2):147-149. |
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| Authors: | Y You C Wu |
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| Institution: | Department of Internal Medicine, Xiangya Hospital, Hunan Medical University, Changsha 410008. |
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| Abstract: | Combination of the anticardiolipin antibody with the phospholipids on the surfaces of the endothelia and thrombocytes can damage the basic functions of cells. In this study, the anticardiolipin antibody was detected in 68 cases with primary nephrotic syndrome and 30 healthy persons. The positive rates were 32.35% and 3.33%, respectively. The hypercoagulability and glomerular impairment in the positive cases were more evident than those in the negative cases. In addition, the sensitivity to treatment in the positive cases was markedly decreased. These findings indicate that the anticardiolipin antibody may play an important role in pathophysiological processes of primary nephrotic syndrome. |
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