卷柏的化学成分

目的研究卷柏Selaginella tamariscina(Beauv.)Spring]的化学成分。方法采用硅胶柱色谱、ODS柱色谱、制备型HPLC等手段进行分离纯化,并利用波谱学方法鉴定化合物的结构。结果从卷柏乙醇提取物中分离得到13个化合物,分别鉴定为3β-羟基-7α-甲氧基-24β-乙基-胆甾-5-烯(1)、胆甾醇(2)、β-谷甾醇(3)、海棠果酸(4)、白桦脂酸(5)、5,4′-二羟基-7-甲氧基黄酮(6)、3-methoxychrysazin(7)、穗花杉双黄酮(8)、异柳杉双黄酮(9)、香草酸(10)、对甲氧基苯甲醛(11)、对羟基苯甲酸(12)、胡萝卜苷(13)。结论化合物1-2、4-7、10、13为本属植物中首次分离得到的化合物。

Chemical constituents of Selaginella tamariscina (Beauv.) Spring

Objective To study the chemical constituents of Selaginella tamariscina (Breauv.) Spring. Methods The compounds were isolated by silica gel, ODS column chromatography, and preparative HPLC and identified by means of the physicochemical and spectral data. Results Thirteen compounds were isolated from the 75%(φ) ethanol extract and identified as 3β-hydroxy-7α-methoxy-24β-ethyl-cholest-5-ene (1), cholesterol (2), β-sitosterol (3), canophyllic acid (4), betulinic acid (5), 5, 4¢-dihydroxy-7-methoxyflavone (6), 3-methoxychrysazin (7), amentoflavone (8), isocryptomerin(9), vanillic acid (10), p-anisaldehyde (11), p-hydroxybenzoic acid (12), and daucosterol (13). Conclusions Compounds 1-2, 4-7, 10, and 13 were isolated from this genus for the first time.