Plasmapheresis and corticosteroid treatment for persistent jaundice after successful drainage of common bile duct stones by endoscopic retrograde cholangiography |
| |
Authors: | Saritas Ulku Aydin Bunyamin Ustundag Yucel |
| |
Institution: | 1. Gastroneterology Department,Süleyman Demirel University, School of Medicine, Turkey 2. Gastroenterology Department, Zonguldak Karaelmas University, School of Medicine, Turkey |
| |
Abstract: | Prolonged cholestasis is a very rare complication of endoscopic retrograde cholangiography (ERC). Only few cases with this complication are reported in the English literature. We report persisting cholestatic jaundice in a 73-year old man after successful therapeutic ERC for choledocholithiasis. Serologic tests for viral and autoimmune hepatitis were all negative. A second-look ERC was normal also. He denied any medication except for prophylaxis given intravenous 1 g ceftriaxon prior to the ERC procedure. After an unsuccessful trial with ursodeoxycholic acid and cholestyramine for 2 wk, this case was efficiently treated with corticosteroids and plasmapheresis. His cholestatic enzymes became normal and intense pruritis quickly resolved after this treatment which lasted during his follow- up period. We discussed the possible mechanisms and treatment alternatives of intrahepatic cholestasis associated with the ERC procedure. |
| |
Keywords: | Endoscopic retrograde cholangiography Cholestasis Plasmapheresis |
本文献已被 维普 万方数据 PubMed 等数据库收录! |