病毒性肝炎的临床与免疫功能的初步研究

<正> 病毒性肝炎(尤其是乙型肝炎)的免疫学研究,虽做了大量工作,但对其免疫病理机制的探讨,依然是众说纷云,问题尚待解决。本文仅就病毒性肝炎的临床转归和某些免疫功能关系的研究,作一初步分析。

Clinical immunoiogical function in Virai hepatitis patients

Sixty-seven inpatients with viral hepatitis entered the study,of whom 48(71.5%) were cured and 19 (28.5%) were not. Almost all the patients with HBsAg negative acute hepatitis were cured (97.4%) when discharged from hospital, while most uncured patients were those suffering from active chronic hepatitis. Therefore, it is very necessary to strengthen the prevention and treatment of chronic hepatitis. The results of the tests showed that the patients with decreased Ea% were as many as 60 out of 61 patients and those with decreased Et% were 54 out of 67 patients, indicating that most of the patients had a decrease in cell-mediated immunity and that increased Es% were seen in cases with chronic and severe hepatitis as well. In addition, the positive rate of CIC was 80% in cases of chronic hepatitis and 52% in acute cases and only a few patients had a decreased C3 level; it was proved that there was HBsAg and anti-HBc in CIC.It was suggested that ClC might have some pathogenic effect.