骨髓基质干细胞的生物学特性与帕金森病的治疗

骨髓基质干细胞(MSCs),具有自我更新和多向分化潜能,可分化为骨细胞、软骨细胞、骨骼肌细胞、心肌细胞、脂肪细胞、神经胶质细胞和神经元等,同时MSCs来源丰富,容易获取,培养简单,免疫源性阴性,可开展自体移植,易转入和稳定表达外源基因,因此,MSCs成为一种较理想的组织工程种子细胞,在治疗帕金森病中具有可观的应用价值。

Marrow Stromal Stem Cells and Parkinson's disease

The marrow stromal stemcells(MSCs) are capable of self-renewal and differentiation into osteocytes,chondrocytes,myocytes, adipocytes,neurogliocyte and neurons.They have rich resource,easy harvesting,simple cultivation,negative immunogenicity,autotransplantation,and can be transfected and express exogenous gene.So marrow stromal stem cells are becoming a kind of ideal tissue engineering cells which have a considerable value in the treatment of degeneration diseases of central nervous system.