| 终末期肝病模型及Child—Pugh分级对失代偿期肝硬化患者的预后分析 |
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| 引用本文： | 占国清,郑三菊,朱琳,王崇慧,李金科,张薇薇. 终末期肝病模型及Child—Pugh分级对失代偿期肝硬化患者的预后分析[J]. 临床肝胆病杂志, 2009, 25(2): 114-116 |
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| 作者姓名： | 占国清 郑三菊 朱琳 王崇慧 李金科 张薇薇 |
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| 作者单位： | 郧阳医学院附属人民医院肝病研究所,湖北,十堰,442000 |
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| 摘 要： | 目的探讨终末期肝病模型（MELD）及Child—Pugh评分对失代偿期肝硬化预后评估的应用价值。方法应用MELD评分公式及Child—Pugh分级对136例失代偿期肝硬化患者进行评分及分级，比较两种系统对肝硬化预后的评估。结果分别有19．85％和33．82％患者3个月和6个月内死亡，死亡组MELD和Child—Pugh评分均高于生存组（P〈0．001）；MELD评分在3个月预后评估的ROC曲线AUC高于Child—Pugh评分（P〈0．05）；生存分析表明MELD与Child—Pugh评分均可有效地分辨6个月内可能生存及死亡的患者（P〈0．005）；MELD评分与Child评分显著相关（r=0．67，P〈0．001）。结论MELD评分及Child—Pugh评分均可预测失代偿期肝硬化患者短期预后，MELD评分短期评估优于Child—Pugh分级。
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| 关 键 词： | 失代偿期肝硬化 MELD评分 Child—Pugh分级 预后 |
The analysis of prognosis of patients with decompensated liver cirrhosis using the criterion of the model for end-stage liver disease and Child-Pugh grading |
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| ZHANG Guo-qing,ZHENG San-ju,ZHU Lin,et al.. The analysis of prognosis of patients with decompensated liver cirrhosis using the criterion of the model for end-stage liver disease and Child-Pugh grading[J]. Chinese Journal of Clinical Hepatology, 2009, 25(2): 114-116 |
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| Authors: | ZHANG Guo-qing ZHENG San-ju ZHU Lin et al. |
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| Affiliation: | Department of Hepatology;People Hospitol;Yunyang Medical College;Shiyan 442000;China |
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| Abstract: | Objective To investigate the prognosis value of the Model for End-stage Liver Disease(MELD)and Child-Pugh grading in patients with decompensated liver cirrhosis.Methods 136 patients with decompensated liver cirrhosis were graded with MELD formula and with Child-Pugh,and the prognosis value were compared.Results 19.85% and 33.82% of the died within three and six month term respectively,MELD and Child-Pugh score for deaths were higher than those for survivors significantly(P<0.001).Area under the ROC of MELD ... |
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| Keywords: | Decompensated liver cirrhosis Model for End-stage Liver Disease scoring Child-Pugh grading Prognosis |
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