广东两个不同地区电信员工幽门螺杆菌感染的血清流行病学调查

目的通过分析广州市与汕尾市两个地区电信员工幽门螺杆菌（Hp）感染的血清学调查资料，以了解广东中心城市与沿海城市的幽门螺杆菌感染的流行差异。方法使用免疫胶体金法对2006年9月至2007年1月来我院进行健康体检的广州市和汕尾市电信员工（共2379人）进行幽门螺杆菌感染的血清学调查。结果广州市与汕尾市两个地区电信员工幽门螺杆菌总感染率分别为23．73％和34．35％，汕尾市幽门螺杆菌总感染率显著高于广州市（Х^2=29．964，P〈0．01）；两个地区电信员工幽门螺杆菌感染率随年龄的增加而增加，51岁以上年龄组为感染率高峰组；广州市男女的阳性率分别为24．82％和20．97％，两者差异无统计学意义（Х^2=2．260，P=0．103）；汕尾市男女的阳性率分别为35．14％和33．65％，两者差异也无统计学意义（Х^2=0．191，P=0．662）。结论广东中心城市电信员工Hp感染率明显低于沿海城市，各地区有必要针对本地区人群开展相应的流行病学调查，制定正确、有效的预防措施。

Epidemiological Survey on Helicobacter pylori Infection of the Telegraphic Employees in Two Different Districts of Guangdong Province

Objective To perform epidemiological study on Helicobacter pylori infection in telegraphic employees in Guangzhou and Shanwei, and to compare the prevalence of H.pylori infection in the coastal and inland cities in Guangdong province. Method 2379 employees from telegraphic companies of Guangzhou and Shanwei were examined between Sep. 2006 and Jan. 2007. Blood samples were obtained for serological analysis by dot immunochromatographic assay. Result The infection rate of H.pylori in Shanwei （34.35%） was significantly higher than Guangzhou （23.73%,Х^2=29.964, P 〈 0.01）. The infection rate was increasing with age in these two districts. The highest infection rate was in the age group older than 51. The positive rate of infection in the male （24.82%） and female subjects （20.97%） was similar in Guangzhou and the difference was not significant （Х^2=2.260, P=0.103）. In Shanwei, the infection rate was 35.14% in the male subjects and 33.65% in the female subjects, and the difference was not significant （Х^2=0.191, P=0.662）. Conclusion In Guangzhou, the incidence of H.pylori infection is markedly lower than Shanwei. Each district should develop their preventive measures for the prevention of infection.