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| 18F-FDG PET/CT结合胸部屏气螺旋CT对肺结节的诊断价值 | |
| 引用本文： | 刘瑛,吴宁,郑容,梁颖,张雯杰,李蒙,赵平.18F-FDG PET/CT结合胸部屏气螺旋CT对肺结节的诊断价值[J].中国医学影像技术,2010,26(1):18-21. |
| 作者姓名： | 刘瑛 吴宁 郑容 梁颖 张雯杰 李蒙 赵平 |
| 作者单位： | 1. 中国医学科学院,北京协和医学院,肿瘤医院PET-CT中心,北京,100021;中国医学科学院,北京协和医学院,影像诊断科,北京,100021 2. 中国医学科学院,北京协和医学院,肿瘤医院PET-CT中心,北京,100021 3. 中国医学科学院,北京协和医学院,影像诊断科,北京,100021 4. 中国医学科学院,北京协和医学院,肿瘤医院PET-CT中心,北京,100021;中国医学科学院,北京协和医学院,腹部外科,北京,100021 |
| 基金项目： | "十一五"国家科技支撑计划课题，北京希望马拉松专项基金，首都医学发展科研基金，高等学校博士学科点专项科研基金，"十一五"新药专项支持 |
| 摘 要： | 目的 评价~(18)F-FDG PET/CT结合胸部屏气螺旋CT扫描对肺结节的诊断价值.方法 154例患者因肺部结节就诊而接受PET/CT检查,其中123例接受双时相PET/CT显像,全部患者先后接受胸部屏气螺旋CT扫描,共发现171个结节.比较PET/CT结合胸部屏气螺旋CT、PET/CT、胸部屏气螺旋CT以及采用SUV_(max)≥2.50作为恶性结节诊断阈值四种方法对恶性结节的诊断效能.所有结果经过组织学、诊断性治疗或临床随诊证实.结果 118个恶性结节SUV_(max常规)为4.51±3.06,53个良性结节SUVmax常规为2.07±1.30.四种方法中,PET/CT结合胸部屏气螺旋CT对恶性结节的诊断灵敏度、特异度、准确率、约登指数最高,分别为95.80%、81.10%、91.20%、0.77.结论 ~(18)F-FDG PET/CT结合胸部屏气螺旋CT对肺结节具有很高的诊断价值. |
| 关 键 词： | 肺肿瘤 肿瘤分期 体层摄影术 发射型计算机 体层摄影术 X线计算机 18F氟脱氧葡萄糖 标准摄取值 诊断 鉴别 |
| 收稿时间： | 2009/9/27 0:00:00 |
| 修稿时间： | 2009/10/10 0:00:00 |
Diagnostic value of 18F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules |
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| LIU Ying,WU Ning,ZHENG Rong,LIANG Ying,ZHANG Wen-jie,LI Meng and XHAO Ping.Diagnostic value of 18F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules[J].Chinese Journal of Medical Imaging Technology,2010,26(1):18-21. | |
| Authors: | LIU Ying WU Ning ZHENG Rong LIANG Ying ZHANG Wen-jie LI Meng and XHAO Ping |
| Institution: | PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China;Department of Abdominal Surgeryy, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China |
| Abstract: | Objective To assess the diagnostic value of ~(18)F-FDG PET/CT combined with breath-hold spiral CT in pulmonary nodules. Methods One hundred and fifty-four patients with 171 pulmonary nodules (≤3 cm) were studied. Each patient underwent ~(18)F-FDG PET/CT (16 slices) examination during mild respiration and breath-hold spiral CT scan, while 123 patients underwent dual-time-point PET/CT examination. The diagnostic efficacy of ~(18)F-FDG PET/CT combined with breath-hold spiral CT,~(18)F-FDG PET/CT, breath-hold spiral CT and taking SUV_(max)≥2.50 as the threshold value for malignancy were compared. All results were proved by pathologically, or by diagnostic therapy or by clinical follow-up. Results The SUV_(max routine) was 4.51±3.06 in 118 malignant nodules, and 2.07±1.30 in 53 benign nodules. The sensitivity, specificity, accuracy and Youdenindex of ~(18)F-FDG PET/CT combined with breath-hold spiral CT was 95.80%, 81.10%, 91.20%and 0.77, respectively, higher than those of other three methods. Conclusion ~(18)F-FDG PET/CT combined with breath-hold spiral CT has high diagnostic value in the differentiation of pulmonary nodules. |
| Keywords: | Lung neoplasms Neoplasm staging Tomography emission-computed Tomography X-ray computed Fluorodeoxyglucose F18 Standardized uptake value Diagnosis differential |
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