芪术汤对慢性鼻-鼻窦炎患者鼻纤毛传输功能的影响

目的:观察芪术汤对慢性鼻-鼻窦炎患者鼻纤毛传输功能的影响。方法:对100例肺脾气虚型慢性鼻-鼻窦炎患者采用芪术汤治疗,以糖精测试法测量患者用药前后的鼻腔黏液纤毛传输时间(MTT)。结果:治疗前测得患者MTT(852±137)s,与健康人群MTT(504±141)s比较,差异有非常显著性意义(P0.01)。治疗后1月,患者MTT(506±92)s,与治疗前比较,差异有非常显著性意义(P0.01),提示鼻纤毛传输功能有明显改善。随访3月、6月,患者MTT分别为(510±137)s和(508±152)s,与健康人群MTT值比较,差异无显著性意义(P0.05)。结论:采用芪术汤治疗肺脾气虚型慢性鼻-鼻窦炎患者,可使患者的鼻纤毛传输功能得到恢复和改善。

Effect of Qizhu Decoction on Nasal Mucociliary Transport of Chronic Rhinosinusitis Patients

Objective： To observe the effect of Qizhu decoction on mucociliary transport function ofchronic rhinosinusitis patients. Methods： One hundred chronic rhinosinusitis patients with the syndrome of lung-spleen Qi deficiency were given Qizhu decoction orally. Saccharin test was used for the measuring of nasal mucociliary transport time（M-i-T） before and after medication. Results： The mean nasal MTT for the chronic rhinosinusitis patients was（852 ＋ 137）seconds, and was（504 ＋ 141） seconds for the healthy volunteers, the difference being significant（P 〈 0.01）. After treatment for one month, the M-IF was （506 ±92）seconds for the patients, differing from that before treatment（P 〈 0.01）. After treatment for 3 and 6 months, the MTT for the patients was（510±＋ 137） and （508± 152） seconds respectively, having no significant difference from that of the healthy volunteers （P 〉 0.05）. Conclusion： Qizhu decoction can improve the nasal mucociliary transport function during the treatment of chronic rhinosinusitis patients with the syndrome of lung-spleen Qi deficiency.