| 血管内皮生长因子-C与肺癌 |
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| 引用本文： | 陈玉,齐协飞.血管内皮生长因子-C与肺癌[J].国际肿瘤学杂志,2007,36(1):434-436. |
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| 作者姓名： | 陈玉 齐协飞 |
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| 作者单位： | 南昌大学第二附属医院呼吸内科,330006; |
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| 摘 要： | 血管内皮生长因子-C(VEGF-C)可以与血管及淋巴管内皮上的特异性受体结合,加速肺癌的形成及转移.同时对恶性胸腔积液的生成、免疫调节因子的表达也有着特殊作用.目前国内外研究均显示VEGF-C的抑制有望成为治疗肺癌的新靶点.
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| 关 键 词： | 血管内皮生长因子C 肺肿瘤 胸腔积液 |
VEGF-C and lung cancer |
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| Abstract: | Vascular endothelial growth factor-C (VEGF-C) binds to special receptors on the vessel and lymphatic endothelium to accelerate the formation and metastasis of lung cancer. It shows specific action on malignant pleural effusion formation and immuno-regulation factor expression. It is reported that inhibition of VEGF-C would be a target point in lung cancer therapy. |
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| Keywords: | Vascular endothelial growth factor CLung neoplasmsPleural effusion |
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