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彩色多普勒超声对卵巢肿瘤内血管的定量分析
引用本文:万小平,苏应宽,刘新民.彩色多普勒超声对卵巢肿瘤内血管的定量分析[J].中华医学杂志,2000,80(9):672-674.
作者姓名:万小平  苏应宽  刘新民
作者单位:山东省立医院妇科(万小平!250021济南,苏应宽!250021济南,刘新民!250021济南),山东省立医院病理科(杜德利!250021济南),山东省医学影像学研究所(王克)
摘    要:

关 键 词:卵巢肿瘤  彩色多普勒超声  免疫组织化学
修稿时间:1999-10-18

Color doppler ultrasound and quantitative histologic study of angiogenesis in ovarian tumors
WAN Xiaoping,SU Yingkuan,LIU Xinmin,et al..Color doppler ultrasound and quantitative histologic study of angiogenesis in ovarian tumors[J].National Medical Journal of China,2000,80(9):672-674.
Authors:WAN Xiaoping  SU Yingkuan  LIU Xinmin  
Institution:Shandong Provincial Hospital, Jinan 250021, China.
Abstract:Objective To investigate whether there is any correlation between minimum resistance index (RImin) and microvessel density (MVD) in ovarian tumors. Methods The intratumor artery RImin of 61 patients with ovarian tumor was measured by color doppler ultra sound (CDU) preoperatively. MVD identified by von Willebrand factor was evaluated postoperatively. The relationship between RImin and MVD was analyzed. Results Compared with the RImin of benign ovarian tumors, the RImin in ovarian cancers was significantly lower ( P <0.001). MVD of ovarian cancer was significantly higher than that of benign tumor both at a 100 magnification ( P < 0.01) and a 400 magnification ( P <0.03). There was a significant negative correlation between RImin and MVD at a 100 magnification in benign group ( r =-0.67, P <0.01), in malignant group ( r =-0.91, P <0 01), and in both of groups ( r =-0.84, P <0.01). Conclusion Low RImin reflects high MVD in ovarian tumor.
Keywords:Ovarian  neoplasms  Neovascularization pathologic  Ultrasonography doppler  color  Immunohistochemistry
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