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| 中性粒细胞明胶酶相关脂质运载蛋白：早期诊断成人心脏术后急性肾损伤的生物学指标（英文） | |
| 引用本文： | 张近波,张小乐,许国斌,董志兵,李传光,王文龙.中性粒细胞明胶酶相关脂质运载蛋白：早期诊断成人心脏术后急性肾损伤的生物学指标（英文）[J].中国临床药理学与治疗学,2010,15(11):1305-1309. |
| 作者姓名： | 张近波 张小乐 许国斌 董志兵 李传光 王文龙 |
| 作者单位： | 1. 温州医学院附属温岭医院EICU,温岭,317500,浙江 2. 河北省滦南县医院血液透析中心,滦南,063500,河北 3. 温州医学院附属温岭医院心内科,温岭,317500,浙江 4. 温州医学院附属温岭医院微创中心,温岭,317500,浙江 5. 温州医学院附属温岭医院肾内科,温岭,317500,浙江 |
| 摘 要： | 心脏术后急性肾损伤的出现会增加患者的死亡率,需要寻找早期诊断急性肾损伤的生物学指标。中性粒细胞明胶酶相关脂质运载蛋白似乎是早期诊断急性肾损伤的生物学指标,它是否能够早期诊断急性肾损伤已经做了广泛的报道。本文综述了已有研究证明它是否能够早期诊断急性 |
| 关 键 词： | 急性肾损伤 中性粒细胞明胶酶相关脂质运载蛋白 生物学指标 心脏手术 |
Neutrophil gelatinase-associated lipocalin: a novel biomarker for the early diagnosis of acute kidney injury following adult cardiothoracic surgery |
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| ZHANG Jin-bo,ZHANG Xiao-le,XU Guo-bin,DONG Zhi-bing,LI Chuan-guang,WANG Wen-long.Neutrophil gelatinase-associated lipocalin: a novel biomarker for the early diagnosis of acute kidney injury following adult cardiothoracic surgery[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2010,15(11):1305-1309. | |
| Authors: | ZHANG Jin-bo ZHANG Xiao-le XU Guo-bin DONG Zhi-bing LI Chuan-guang WANG Wen-long |
| Institution: | 1Department of EICU,Wenling Hospital Affiliated to Wenzhou Medical College,Wenling 317500,Zhejiang,China;2Hebei Luan nan Hospital,Luannan 063500,Hebei,China;3Department of Cardiology,Wenling Hospital Affiliated to Wenzhou Medical College,4 Centre of Microtrauma,5 Department of Nephrology,Wenling 317500,Zhejiang,China |
| Abstract: | It is needed to develop early bio-markers of acute kidney injury following cardiac surgery, whose morbidity and mortality are increased by its presence. NGAL( neutrophil gelatinase-associated lipocalin) seems to be a promising biomarker for the early diagnosis of acute kidney injury (AKI). However, a wide range in its predictive value has been reported. It is reviewed whether NGAL can early diagnosis AKI actually. |
| Keywords: | Acute kidney injury Neutrophil gelatinase-associated lipocalin Biomarker Cardiothoracic surgery |
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