3种用药方案治疗下呼吸道感染的成本-效果分析

目的探讨3种不同治疗方案用于下呼吸道感染的经济效果。方法运用药物经济学成本-效果分析法对A组(左氧氟沙星口服)、B组(阿奇霉素口服)、C组(左氧氟沙星 阿奇霉素口服)进行回顾性分析评价。结果3种药物治疗方案成本分别为34.8元、56元、59.3元;细菌清除率分别为85.19%、80.77%、92.8%(P>0.05);痊愈率分别为65.6%、59.4%、75%(P>0.05);成本-效果比分别为(细菌清除率)0.41、0.69、0.64;(痊愈率)0.40、0.72、0.63;有效率分别为87.5%、78.125%、93.75%(P<0.05);3种方案治疗下呼吸道感染在痊愈率、细菌清除率上无显著差异,在有效率上有显著差异。结论综合考虑,C方案为较佳方案。

Cost-effectiveness analysis of 3 therapeutic schemes in treatment of lower respiratory tract infections

Objective To probe into the economic-effectiveness of different therapeutic schemes in the treatment of lower respiratory tract infections. Methods We retrospectively conducted a cost-effectiveness analysis on three groups of patients using different medication schemes. Group A used levofloxacin by oral administration,Group B used azithromycin by oral administration and Group C used levofloxacin and azithromycin by oral administration.Results For Group A,B and C,the costs were respectively 34.8 yuan,56 yuan and 59.3 yuan; the germ clearance rates were respectively 85.19%,80.77% and 92.86% (P<0.05); the cure rates were respectively 65.6%,59.4% and 75% (P<0.05); the incidences for adverse effects were respectively 9.4%,6.25% and 12.5% (P<0.05); the cost-effectiveness ratio (germ-clearance rates) were respectively 0.41,0.69 and 0.64; the cure rates were respectively 0.40,0.72 and 0.63; the effective rates were 87.5%,78.13 and 93.75% (P<0.05). There was no statistical differences among the three groups in terms of the cure rate and germ-clearance rate,and there was significant difference in the effectiveness rate. Conclusion In comparison,Group C has better overall effect than the other two.