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Determinants of pharmacodynamic trajectory of the therapeutic response to paroxetine in Japanese patients with panic disorder |
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| Authors: | Shin Ishiguro Takashi Watanabe Mikito Ueda Yoshinori Saeki Yuki Hayashi Kazufumi Akiyama Atsushi Saito Kazuko Kato Yoshimasa Inoue Kazutaka Shimoda |
| Affiliation: | (1) Department of Psychiatry, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotsuga Tochigi, 321–0293, Japan;(2) Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotsuga Tochigi, 321–0293, Japan;(3) Sakura La Mental Clinic, 6-13-16 Youtou, Utsunomiya Tochigi, 321–0904, Japan;(4) Mitsubishi Tanabe Pharma Factory Ltd, 955 Koiwai, Yoshitomicho, Chikujo, Fukuoka 871–8550, Japan |
| Abstract: | PurposeThe objective of this study was to evaluate genetic and pharmacokinetic factors to establish the pharmacotherapeutic effect of paroxetine (PAX) in patients with panic disorder (PD). |
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