新生儿呼吸机相关肺炎的病原菌分析

目的:探讨新生儿呼吸机相关肺炎(VAP)的病原学和药物敏感情况,指导临床用药.方法:符合VAP诊断标准的31例患儿的气道分泌物培养和药敏试验进行回顾性分析.结果:16例痰培养阳性,共检出细菌23株,其中革兰阴性杆菌12株,球菌6株,霉菌5株.结论:VAP的病原菌以革兰阴性菌为主,对亚胺硫霉素较敏感,其次为环丙沙星、头孢吡肟.混合感染和多重耐药是VAP的病原学特点.

Analysis of pathogenic bacteria of ventilator-associated pneumonia in neonates

Objective:To investigate the etiology of ventilator-associated pneumonia(VAP) and its drug sensitivity condition,so as to instruct the clinical treatment.Methods:The airway secretion culture and drug sensitivity test in 31 sick chlidren who met the diagnostic criterion of VAP were analysed retrospectively.Results:The sputum culture was positive in 16 cases,and 28 strains of bacterium were detected in all.Of 28 strains,12 were gram-negative bacillus, 6 coccus and 5 fungus.Conclusion:The main pathogenic bacteria of VAP are gram-negative bacteria,and are relatively sensitive to adriamycin and then ciprofloxacin and cefepime.The mixed infection and multiplet drug resistance are the etiological characteristics of VAP.