CT灌注成像在脑内缺血性疾病中的初步应用

目的 评价ＣＴ灌注成像在脑内缺血性疾病的作用。方法 对２４例缺血性中风发作２小时至２个月的患者及１０例开颅术后的患者行常规ＣＴ扫描及ＣＴ灌注成像，２８例进行ＭＲＩ检查，６例行ＤＳＡ检查及单光子发射计算机体层成像（ｓｉｎｇｌｅ ｐｈｏｔｏｎｅｍｉｓｓｉｏｎ ｃｏｍｐｕｔｅｄ ｔｏｍｏｇｒａｐｈｙ，ＳＰＥＣＴ）。结果 ３４例患者ＣＴ扫共检出３０个缺血及梗死灶，ＣＴ灌注成像共检出４１个病灶，均经随访Ｃ

The preliminary research of CT perfusion imaging in intraaxial ischemic disease

Objective To evaluate the application of CT perfusion in intraaxial disease Methods 34 cases intracranial ischemic disease (including 24 cases with stroke, 10 cases with postoperation ischemic lesions) were analyzed 19males, 15 females 34 cases with CT imaging and CT perfusion imaging, 28 cases with MRI examination, 6 cases with DSA snd SPECT examination Results There were 41 ischemic lesions on CT perfusion imaging, conformed by followup CT, MRI and SPECT images While only 30 on regular CT images 40 lesions with PT (longer peak time) and MTT (mean transit time), and lower RF (relative flow ) than opposite's, P<00001 Only one lesion-2 weeks after stroke onset with shorter PT and MTT and higher RF Conclusions Combined with regular CT and MRI images, CT perfusion imaging not only is useful in demonstrating the hyperacute ischemic stroke, but also can show the hemodynamic changes of intraaxial ischemic lesions caused by moya moya disease and craniotomy.