Bidentatoside I, a new triterpene saponin from Achyranthes bidentata. |
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Authors: | A C Mitaine-Offer A Marouf C Pizza T C Khanh B Chauffert M A Lacaille-Dubois |
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Affiliation: | Laboratoire de Pharmacognosie, Unité MIB, J E 2244, Faculté de Pharmacie, Université de Bourgogne, 7 Bd. Jeanne D'Arc, BP 87900, 21079 Dijon, France. |
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Abstract: | Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line. |
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