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Bidentatoside I, a new triterpene saponin from Achyranthes bidentata.
Authors:A C Mitaine-Offer  A Marouf  C Pizza  T C Khanh  B Chauffert  M A Lacaille-Dubois
Affiliation:Laboratoire de Pharmacognosie, Unité MIB, J E 2244, Faculté de Pharmacie, Université de Bourgogne, 7 Bd. Jeanne D'Arc, BP 87900, 21079 Dijon, France.
Abstract:Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.
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