| MTT法测定异博定逆转胃癌与结肠癌细胞多药物抗性的研究 |
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| 引用本文： | 沈守荣,赵善灿.MTT法测定异博定逆转胃癌与结肠癌细胞多药物抗性的研究[J].中国现代医学杂志,1996,6(1):1-3. |
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| 作者姓名： | 沈守荣 赵善灿 |
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| 作者单位： | 湖南医科大学附属湘雅医院内科!410008 |
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| 摘 要： | 用MTT法测定了钙通道阻滞剂异博定逆转胃癌和结肠癌的多药物抗性。结果表明异博定能有效地提高5－Fu、MMC、CDDP和ADM的细胞毒性作用，增强这些化疗药物杀伤肿瘤细胞的作用。
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| 关 键 词： | MTT法 异博定 癌细胞 逆转多药物抗性 化疗药物 |
REVERSAL OF MULTIDRUG RESISTANCE IN GASTRIC AND COLON CANCER CELLS BY VERAPAMIL USING MTT ASSAY |
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| Shen Shourong,et al..REVERSAL OF MULTIDRUG RESISTANCE IN GASTRIC AND COLON CANCER CELLS BY VERAPAMIL USING MTT ASSAY[J].China Journal of Modern Medicine,1996,6(1):1-3. |
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| Authors: | Shen Shourong |
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| Institution: | Shen Shourong, et al. |
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| Abstract: | Using the MGC cells from gastric cancer and the HRT-18 cells from colon cancer as the target cells it wins revealcd that the reversal of multidrug resistance by calcium channel blocker verapamil was studied by MTT assay. The results showed that verapamil can increase the cytotoxity of anticancer drugs 5-Fu, MMC, CDDP and ADM. |
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| Keywords: | MTT assay |
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