| 羚羊角与山羊角药理作用比较 |
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| 引用本文： | 姜清华,翟延君. 羚羊角与山羊角药理作用比较[J]. 实用口腔医学杂志, 2006, 34(7): 582-583 |
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| 作者姓名： | 姜清华 翟延君 |
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| 作者单位： | 中国医科大学附属第二医院，辽宁中医药大学药学院 110004 |
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| 摘 要： | 目的通过羚羊角和山羊角水溶性成分的镇痛和解热作用比较,探索山羊角作为羚羊角替代品的可能性。方法应用热板法、扭体法及伤寒Vi多糖菌苗造模法。结果羚羊角和山羊角能明显减少冰醋酸引起的小鼠扭体次数(P<0.01)和明显提高小鼠痛阈值(给药后60 min,P<0.05);能明显降低伤寒Vi多糖菌苗引起的发热。结论山羊角与羚羊角均有镇痛和解热作用,因此山羊角替代羚羊角具有可行性。
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| 关 键 词： | 羚羊角 镇痛 山羊角 解热 |
| 收稿时间： | 2006-03-31 |
| 修稿时间： | 2006-03-31 |
Pharmacological action comparison between Cornu antelopis and Cornu caprae hircus |
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| JIANG Qing-hua,ZHAI Yan-jun. Pharmacological action comparison between Cornu antelopis and Cornu caprae hircus[J]. Journal of Practical Stomatology, 2006, 34(7): 582-583 |
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| Authors: | JIANG Qing-hua ZHAI Yan-jun |
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| Affiliation: | Second Affiliated Hospital, China Medical University, Shenyang 110004 ,China |
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| Abstract: | Objective To compare the pharmacological action of relieving pain and fever of water-soluble compositions in Cornu antelopis and Cornu caprae hircus and to explore if the latter can replace the former.Methods Woolfe-MacDonald,writhing method was used and models were made with lipolysaccharide vaccine.Results Cornu antelopis and Cornu caprae hircus could decrease the writhing times of mice caused by glacial acetic acid(P<0.01),obviously increase the pain threshold value of mice (P<0.05 after 60 min),and decrease the temperature caused by vipolysaccharide vaccine.Conclusion Cornu antelopis and Cornu caprae hircus both can relieve pain and fever,so the Cornu caprae hircus is able to substitute the Cornu antelopis. |
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| Keywords: | Cornu antelopis Analgesia Cornu caprae hircus Defevescence |
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