New insights into insulin resistance pathophysiology: how it affects glucose and lipid metabolism |
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Authors: | Col V |
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Affiliation: | Centre Hospitalier Jolimont-Lobbes, Rue Ferrer, 159, B-7100 Haine-St-Paul, Belgium. vcol@wanadoo.be |
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Abstract: | Insulin resistance is a metabolic state encountered in many physiological and physiopathological conditions. Its pivotal effect on glucose and lipid metabolism is increasingly recognised. Over the last few years, numerous molecular/intracellular pathways affected by this condition have been elucidated. The author reviews some recent findings underlying several major metabolic abnormalities. An overview of current and future therapeutics is also provided. |
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