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Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells |
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| Authors: | Kuroda M Mimaki Y Sashida Y Umegaki E Yamazaki M Chiba K Mohri T Kitahara M Yasuda A Naoi N Xu Z W Li M R |
| Abstract: | The MeOH extract of Epimedium sagittatum was found to show neurite outgrowth activity on cultured PC12h cells. Bioassay-guided fractionation of the MeOH extract yielded six prenylated flavonol glycosides, ikarisoside A (1), icarisid II (2), epimedoside A (3), icariin (4), epimedin B (5), and epimedokoreanoside-I (6) as the active ingredients. |
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