| 2型糖尿病慢性并发症中血脂的变化及其意义 |
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| 引用本文： | 李娟,徐家新,王春,吕高友,金国玺.2型糖尿病慢性并发症中血脂的变化及其意义[J].蚌埠医学院学报,2015,40(12):1649-1651. |
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| 作者姓名： | 李娟 徐家新 王春 吕高友 金国玺 |
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| 作者单位： | 蚌埠医学院第二附属医院 内分泌科,安徽 蚌埠,233040;蚌埠医学院第一附属医院 儿科,安徽 蚌埠,233004;蚌埠医学院第一附属医院 内分泌科,安徽 蚌埠,233004 |
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| 摘 要： | 目的:探讨血脂、载脂蛋白与2型糖尿病慢性并发症的关系及其意义. 方法:选择65例2型糖尿病患者为病例组,同期健康体检者57名为对照组,受试者均禁食12 h以上,清晨空腹抽取静脉血,采用全自动生化仪测定血脂及载脂蛋白,并进行相关统计学分析. 结果:2型糖尿病患者血清胆固醇、三酰甘油、低密度脂蛋白、载脂蛋白B及载脂蛋白B/载脂蛋白A1水平均显著高于对照组(P<0. 01),而高密度脂蛋白和载脂蛋白A1水平均明显低于对照组(P<0. 01). 结论:2型糖尿病血脂异常明显,早期血脂干预治疗有着非常重要的意义.
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| 关 键 词： | 糖尿病 2型 血脂 载脂蛋白 |
The change of serum lipids level in type 2 diabetes mellitus complicated with chronic complication and its significance |
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| Abstract: | Objective:To explore the relationships between the blood lipids,apolipoprotein and type 2 diabetes mellitus complicated with chronic complication,and its significance. Methods:Sixty-five type 2 diabetic patients and 57 healthy people were divided into the case group and control group,respectively. The levels of serum lipids and apolipoproteins in morning fasting venous blood of two groups after 12 h of fasting were measured by automatic biochemical analyzer, and analyzed statistically. Results:The serum levels of triglyceride,total cholesterol, low density lipoprotein, apolipoprotein B and ratio of apolipoprotein B/apolipoprotein A1 in case group were significantly higher than those in control group(P<0. 01),while the serum levels of high density lipoprotein and apolipoprotein A1 in case group were significantly lower than those in control group(P<0. 01). Conclusions:The blood lipid level in type 2 diabetes mellitus is obviously abnormal,and the early intervention treatment of blood lipid has very important significance. |
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| Keywords: | diabetes mellitus type 2 blood lipid apolipoprotein |
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