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前列地尔联合甲钴胺治疗糖尿病周围神经病变的临床观察
引用本文:马咏梅,费小薇,徐邦奎.前列地尔联合甲钴胺治疗糖尿病周围神经病变的临床观察[J].实用临床医药杂志,2011,15(19):103-104,107.
作者姓名:马咏梅  费小薇  徐邦奎
作者单位:江苏省泰州市人民医院内分泌科,江苏泰州,225300
基金项目:中国高校医学期刊临床专项资金资助项目
摘    要:目的探讨前列地尔联合甲钴胺治疗糖尿病周围神经病变(DPN)的疗效及安全性。方法将60例糖尿病周围神经病变患者分为治疗组(n=30)和对照组(n=30)。治疗组静脉注射前列地尔针剂10μg+肌肉注射甲钴胺500μg,1次/d;对照组单用甲钴胺500μg,1次/d,共2周。结果治疗组DPN症状体征、神经传导速度改善显著优于对照组。结论前列地尔与甲钴胺联合应用可显著提升糖尿病周围神经病变的治疗效果。

关 键 词:凯时  甲钴胺  糖尿病周围神经病变  疗效

The observation of Alprostadil combined with Methylcobalamin in the treatment of diabetic peripheral neuropathy
MA Yong-mei,FEI Xiao-wei,XU Bang-kui.The observation of Alprostadil combined with Methylcobalamin in the treatment of diabetic peripheral neuropathy[J].Journal of Clinical Medicine in Practice,2011,15(19):103-104,107.
Authors:MA Yong-mei  FEI Xiao-wei  XU Bang-kui
Institution:(Taizhou People′s Hospital,Taizhou,Jiangsu,225300)
Abstract:Objective To study the safety and efficacy of Alprostadil,a joint cobalt in the treatment of diabetes amine peripheral neuropathy.Methods Sixty patients with diabetic peripheral neuropathy were divided into treatment group(n=30) and control group(n=30).The treatment group was injected with Alprostadil 10 μg + intramuscular injection of Methylcobalamin 500 μg,1 times/d.The control group received Methylcobalamin 500 μg alone,1 times/d.The treatment was two weeks.Results Symptoms and signs,nerve conduction velocity of the treatment group improved significantly than those of the control group.Conclusion Alprostadil combined with Methylcobalamin can significantly improve the treatment of diabetic peripheral neuropathy effect.
Keywords:Alprostadil  Methylcobalamin  diabetic peripheral neuropathy  efficacy  
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