| 埃索美拉唑与莫沙必利联用治疗胃食管反流病疗效观察 |
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| 引用本文： | 季文锋.埃索美拉唑与莫沙必利联用治疗胃食管反流病疗效观察[J].实用临床医药杂志,2011,15(15):89-90,93. |
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| 作者姓名： | 季文锋 |
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| 作者单位： | 江苏省阜宁县人民医院,江苏阜宁,224400 |
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| 摘 要： | 目的探讨埃索美拉唑与莫沙必利联用治疗胃食管反流病(GERD)的疗效。方法 80例GERD患者,采用随机双盲法分成2组,治疗组40例,给予埃索美拉唑40 mg/d,莫沙必利5 mg,3次/d,口服。对照组40例,给予埃索美拉唑40mg/d,口服,于治疗后6周观察胃烧心、反流、反酸、非心源性胸痛等症状的缓解情况,并于6周后复查胃镜,观察食管炎治愈率,总有效率。结果治疗组治疗6周后总有效率95%,对照组治疗6周后总有效率80%,2组比较有极显著性差异(P<0.01);治疗组治疗6周后内镜下A、B、C、D级食管炎治愈率达70%,总有效率90%,对照组治疗6周后内镜下A、B、C、D级食管炎治愈率57.5%,总有效率75%,2组比较有极显著性差异(P<0.01)。结论埃索美拉唑与莫沙必利联用是治疗胃食管反流病的有效方案。
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| 关 键 词： | 胃食管反流病 埃索美拉唑 莫沙必利 |
Esomeprazole and Mosapride in the treatment of gastroesophageal reflux disease |
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| JI Wen-feng.Esomeprazole and Mosapride in the treatment of gastroesophageal reflux disease[J].Journal of Clinical Medicine in Practice,2011,15(15):89-90,93. |
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| Authors: | JI Wen-feng |
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| Institution: | JI Wen-feng(Funing People′s Hospital,Funing,Jiangsu,224400) |
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| Abstract: | Objective To investigate the effect of Esomeprazo1e and Mosapride in the treatment of gastroesophageal reflux disease(GERD).Methods Eighty patients with GERD,based on a randomized double-blind method,was divided into two groups.The treatment group of 40 patients was given Esomeprazole 40 mg/day,Mosapride 5 mg,orally taken 3 times a day.Control group of 40 patients orally took Esomeprazole 40 mg/day.Six weeks after treatment,stomach heartburn,reflux,and anti-acid,non-cardiac chest pain and other symptoms of ... |
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| Keywords: | gastroesophageal reflux disease Esomeprazole Mosapride |
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