同型半胱氨酸与急性脑梗死近期预后的关系

目的：探讨血浆同型半胱氨酸（Hcy）与急性脑梗死近期预后的关系。方法：测定291例急性脑梗死患者空腹Hcy，并以此结果将患者分为Hcy升高者为观察组和正常者为对照组，对两组患者神经功能缺损、日常生活能力及脑梗死的复发情况进行追踪观察。结果：观察组和对照组在入院时、发病14d神经功能缺损和日常生活能力评分差异无显著性（P〉．0．05），在发病后30d、180d观察组神经功能缺损评分显著高于对照组，生活能力评分显著低于正常组，1年内脑梗死的复发率显著高于正常组（P〈0．05）。结论：高Hcy血症对脑梗死患者的恢复存在不良影响，并且使复发的危险性增加。

Relationship Between Plasama Homocysteine and short term Prognosis of Acute Cerebral Infarction

Objective：To study the relationship between plasma homocysteine（Hcy） and short term prognosis of acute cerebral infarction. Methods：We measureed the plasma Hcy of 291 patients with acute cerebral infarction, then we divided the patients into H hcy （homocysteinemia） group and normal group on the basis of the examming outcome. We observed the neural deficit ability of daily life and recurrence rate of cerebral infarction. Results：There was no statistical difference between the 2 groups in the neural deficit score and ability score of daily life on the admission and 14 d of onset （P〉0.05）. On 30 d, 180 d,the neural deficit score of the H hcy group respectively was significantly higher than that of the normal group, the ability score of daily life was opposite （P〈0.05）, and the recurrence rate of cerebral infarction of H hcy group was also significantly higher than that of the normal group（P〈0.01）. Conclusion：H hcy is harmful to the rehabilitation of the patients with acute cerebral infarction, and increases recurrence risk of cerebral infarction.