Diagnosis and evolution of periventricular leukomalacia: a study with real-time ultrasound |
| |
Authors: | Tzipora Dolfin Martin B. Skidmore Katherine W. Fong Elizabeth M. Hoskins Andrew T. Shennan Alan Hill |
| |
Affiliation: | 1. Regional Perinatal Unit, Women''s College Hospital, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada;1. Department of Radiology, Women''s College Hospital, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada;2. Department of Neurology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M591X8, Canada |
| |
Abstract: | Periventricular leukomalacia is an ischemic lesion in periventricular white matter of premature infants. Hemorrhage into the ischemic area occurs in up to 25% of cases. We report two cases in which the diagnosis of periventricular leukomalacia was made during life with real-time ultrasound scanning. In one case, serial scans demonstrated the evolution of echodense regions, observed in the first 3 days of life, to cystic echolucent areas at 4 weeks. In the second case, periventricular echodense areas did not precede the occurrence of cystic echolucent lesions. This may reflect a more chronic ischemic cerebral insult (consistent with recurrent apnea and bradycardia) rather than a presumed acute episode of cerebral ischemia (with or without secondary hemorrhage) sustained by the first case. Real-time ultrasound scanning is a simple, non-invasive technique with which to document the evolution of periventricular leukomalacia, and thus to define the clinical neurological correlates in the neonatal period. |
| |
Keywords: | periventricular leukomalacia real-time ultrasound |
本文献已被 ScienceDirect 等数据库收录! |
|