| 中药金铁锁中一个新的环七肽 |
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| 引用本文： | 黄建华,肖建青,刘锡葵.中药金铁锁中一个新的环七肽[J].中国实验方剂学杂志,2013,19(22):120-123. |
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| 作者姓名： | 黄建华 肖建青 刘锡葵 |
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| 作者单位： | 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室, 昆明 650201;中国科学院大学, 北京 100049;中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室, 昆明 650201;中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室, 昆明 650201 |
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| 摘 要： | 目的: 研究中药金铁锁中的化学成分。 方法: 利用葡聚糖凝胶Sephadex LH-20、硅胶、RP-18反相柱、中压等色谱方法进行化合物的分离纯化,根据化合物的理化性质、光谱数据进行结构鉴定。 结果: 从中药金铁锁中分离得到两个环七肽成分,tunicyclin C (1)和tunicyclin K (2)。 结论: Tunicyclin K 为一个新的天然产物。
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| 关 键 词： | 环七肽 金铁锁 结构鉴定 |
| 收稿时间： | 2013/3/20 0:00:00 |
A New Cycloheptapeptide from Psammosilene tunicoides |
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| HUANG Jian-hu,XIAO Jian-qing and LIU Xi-kui.A New Cycloheptapeptide from Psammosilene tunicoides[J].China Journal of Experimental Traditional Medical Formulae,2013,19(22):120-123. |
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| Authors: | HUANG Jian-hu XIAO Jian-qing and LIU Xi-kui |
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| Institution: | State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;University of the Chinese Academy of Sciences, Beijing 100049, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China |
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| Abstract: | Objective: To study the chemical constituents of the roots of Psammosilene tunicoides. Method: The chemical constituents were isolated and purified via silica gel, Sephadex LH-20 column chromatography, RP-18 column and MPLC. Their structures were identified on basis of spectral data and chemical methods. Result: Two cycloheptapeptides were isolated from the roots of P. tunicoides, tunicyclin C (1) and tunicyclin K (2). Conclusion: Tunicyclin K was a new natural product. |
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| Keywords: | cycloheptapeptide Psammosilene tunicoides structure identification |
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