血清降钙素原在儿童细菌感染性疾病诊断中的意义

目的探讨血清降钙素原（PCT）测定在儿童细菌感染性疾病中的诊断意义。方法收集各种儿童感染性疾病患儿129例，将其分为细菌感染和非细菌感染组。采用半定量的胶体金免疫结合法检测PCT，免疫比浊法测定C-反应蛋白（CRP）。结果细菌感染组PCT、CRP阳性率分别为90．0％、80．0％，非细菌感染组阳性率分别为21．3％、65．2％，两组比较PCT差异有统计学意义（P〈0．01）；CRP差异无统计学意义（P〉0．05）。结论在儿童细菌感染性疾病诊断中，PCT检测可作为早期快速鉴别细菌感染的实验室新指标。

Clinical significance of procalcitonin measurement of bacterial infectious diseases in children

Objective To explore the diagnostic significance of proealationin（PCT） in children＇s bacterial infectious diseases. Methods 129 cases of children＇s infectious diseases were collected and divided into bacterial infection group and non--bacterial infection group. PCT and CRP were detected by semi-quantitative colloidal gold immunobindingmetry and immunoturbidimetry,respeetively. Results The positive rate of serum of PCT and CRP in bacterial infection group was 90.0% and 80.0% respectively,while in non--bacterial infection group it was 21.3% and 65.2 % ,respectively. Levels of PCT in bacterial infection group were significantly higher than that in non-bacterial infeetion（P〈0.01） ,differences were not found in CRP between the two groups（P〉0.05）. Conclusion PCT could be used as a new diagnostic marker for rapid identification of bacterial infectious in early stage of children＇s infectious diseases.