No association between transmembrane protein-tyrosine phosphatase receptor type C (PTPRC) exon A 77C>G transversion and liver transplant rejection |
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| Authors: | Thude H Schipler A D Treszl A Sterneck M Nashan B |
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| Affiliation: | 1. Department of Hepatobiliary and Transplant Surgery, University Hospital Hamburg‐Eppendorf, Hamburg, Germany;2. Department of Medical Biometry and Epidemiology, University Hospital Hamburg‐Eppendorf, Hamburg, Germany |
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| Abstract: | This study was carried out to evaluate the association between 77C>G transversion (rs17612648) in exon A of the PTPRC gene and liver transplant rejection. No significant differences in genotype and allele frequencies of the 77C>G transversion were detected between recipients without rejection (n = 106) and recipients with rejection (n = 104). In conclusion, there was no evidence for the contribution of the 77C>G transversion in susceptibility to liver transplant rejection in a Caucasian population. |
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