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颈动脉粥样硬化性狭窄患者血管内皮生长因子检测及意义
引用本文:朱其秀,卢瑞春,谭兰,宋敬卉. 颈动脉粥样硬化性狭窄患者血管内皮生长因子检测及意义[J]. 中风与神经疾病杂志, 2007, 24(5): 596-597
作者姓名:朱其秀  卢瑞春  谭兰  宋敬卉
作者单位:1. 青岛大学医学院附属医院康复医学科,山东,青岛,266003
2. 青岛大学医学院附属医院神经内科,山东,青岛,266003
摘    要:目的探讨颈动脉粥样硬化性狭窄(CAS)患者血管内皮生长因子(VEGF)水平变化。方法用酶联免疫法测定73例颈动脉粥样硬化性狭窄(CAS)患者和40例正常对照组血清中VEGF的水平。结果CAS组VEGF水平均高于正常对照组(P<0.05)。结论颈动脉粥样硬化性狭窄患者的血清VEGF水平明显升高。血清VEGF高水平可能成为CAS出现及以后发展为缺血性脑卒中的预测因素和危险因素之一。

关 键 词:颈动脉粥样硬化性狭窄  缺血性脑卒中  内皮生长因子
文章编号:1003-2754(2007)05-0596-02
修稿时间:2007-04-04

Clinical significance of measurement of plasma vascular endothelial growth factor (VEGF) levels in patietns with carotid artery stenosis
ZHU Qi-xiu LU Rui-chun TAN Lan. Clinical significance of measurement of plasma vascular endothelial growth factor (VEGF) levels in patietns with carotid artery stenosis[J]. Journal of Apoplexy and Nervous Diseases, 2007, 24(5): 596-597
Authors:ZHU Qi-xiu LU Rui-chun TAN Lan
Abstract:Objective Objective To investigate the plasma VEGF levels in patients with carotid artery steno- sis.Methods Plasma VEGF were measured with ELISA in 73 cases of carotid artery stenosis and 40 cases of con- trols.Results In carotid artery stenosis,plasma levels of VEGF were signifi-cantly higher than those controls(P<0.05).Conclusion The plasma VEGF level in patients with carotid artery stenosis is significantly high-er than normal.The high level of plasma VEGF will forecast and contribute the development of cerebral ischemic stroke.
Keywords:Carotid artery stenosis  Cerebral ischemic stroke  Vascular endothelial growth factor
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