艾滋病合并结核病近期临床疗效观察

目的 探讨艾滋病合并结核病的诊断及治疗的近期疗效。方法 对河南省某局部地区98例艾滋病合并结核病患者的临床资料进行分析。结果 98例艾滋病合并结核病患者以发热、咳嗽、盗汗、体质量降低、浅表淋巴结肿大、呼吸困难为常见症状。采用鸡尾酒疗法抗病毒治疗以及6个月短程方案2SHRZ／4HRZ抗结核治疗S(链霉素)、H(异烟肼)、R(利福平)、Z(吡嗪酰胺)]，病人临床症状、体征、病灶吸收率、空洞好转率、免疫功能均有改善。结论 结核科医师应加强对HIV合并结核诊断的认识。痰涂片检查抗酸杆菌及X线检查仍具有较好的诊断价值，结核病诊断及结核菌素试验阴性不能排除结核，短期抗结核治疗具有一定效果。

Diagnosis and short-term therapeutic effect of AIDS complicated by tuberculosis]

OBJECTIVE: To investigate the shore-term therapeutic effects of AIDS complicated by tuberculosis. METHODS: Ninety-eight AIDS patients with tuberculosis living in a village in Henan province were observed. RESULTS: Among the 98 patients, fever, cough, night sweating, weight loss, and superficial lymph node swelling were the common symptoms. Highly active anti-retroviral therapy (HAART) combined with a 6-month anti-tuberculosis treatment protocol with streptomycin, isoniazid, rifampin, and pyrazinamide (2SHRZ/4HRZ) resulted in improvement of the patients' clinical symptoms and signs as well as the immune functions. CONCLUSION: AIDS complicated by tuberculosis should receive due medical attention and sputum smear examination for anti-acid bacillus combined with X-ray examination possesses good diagnostic value for tuberculosis in these patients, for whom short-term anti-tuberculosis treatment may have beneficial effects.