|
|||||
|
|
The influence of brain tissue anisotropy on human EEG and MEG. |
|
| Authors: | J Haueisen D S Tuch C Ramon P H Schimpf V J Wedeen J S George J W Belliveau |
| Institution: | 1. Department of Radiology, Mount Sinai Medical Center, Miami Beach, FL and Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA;2. Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA;3. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA;4. Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA;5. Department of Neurology, University of Massachusetts Medical School, Worcester, MA |
| Abstract: | The influence of gray and white matter tissue anisotropy on the human electroencephalogram (EEG) and magnetoencephalogram (MEG) was examined with a high resolution finite element model of the head of an adult male subject. The conductivity tensor data for gray and white matter were estimated from magnetic resonance diffusion tensor imaging. Simulations were carried out with single dipoles or small extended sources in the cortical gray matter. The inclusion of anisotropic volume conduction in the brain was found to have a minor influence on the topology of EEG and MEG (and hence source localization). We found a major influence on the amplitude of EEG and MEG (and hence source strength estimation) due to the change in conductivity and the inclusion of anisotropy. We expect that inclusion of tissue anisotropy information will improve source estimation procedures. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |