A prognostic approach on a case of pediatric Philadelphia chromosome‐positive acute lymphoblastic leukemia with monosomy‐7 |
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| Authors: | Hanaa Skhoun Mohammed Khattab Aziza Belkhayat Zahra Takki Chebihi Nadia Dakka Jamila El Baghdadi |
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| Affiliation: | 1. Genetics Unit, Military Hospital Mohammed V, Rabat Morocco ; 2. Laboratory of Human Pathologies Biology, Genomic Center of Human Pathologies, Faculty of Sciences, Mohammed V University in Rabat, Rabat Morocco ; 3. Department of Pediatric Hemato‐Oncology, Children''s Hospital of Rabat, Rabat Morocco ; 4. BIOLAB Laboratory, Rabat Morocco |
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| Abstract: | In this work, we present the first case of a Ph‐positive ALL Moroccan girl with t(9;22)(q34;q11) and monosomy‐7. She was diagnosed with Ph‐positive ALL based on bone marrow examination, immunophenotyping, and cytogenetic analysis. She relapsed after treatment with the persistence of the Ph chromosome and the appearance of a monosomy‐7. |
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| Keywords: | ALL, childhood, monosomy‐ 7, patient outcome, Philadelphia‐ Positive |
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