Comparison of fundamental sonography, tissue-harmonic sonography, fundamental compound sonography, and tissue-harmonic compound sonography for focal hepatic lesions |
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Authors: | Se Hyung Kim Jeong Min Lee Kwang Gi Kim Jong Hyo Kim Joon Koo Han Jae Young Lee Byung Ihn Choi |
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Institution: | (1) Department of Radiology, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, South Korea;(2) Institute of Radiation Medicine, Seoul National University Hospital, Seoul, South Korea;(3) Department of Medical Engineering, Seoul National University Hospital, Seoul, South Korea |
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Abstract: | Image qualities of fundamental, tissue-harmonic, fundamental compound, and tissue-harmonic compound sonography for evaluating
focal hepatic lesions were compared. Two radiologists, blinded to the type of techniques and to the final diagnosis, independently
evaluated 384 images of 96 hepatic lesions: hemangiomas (n=35), hepatic cystic lesions (n=28), cirrhosis-related nodules (n=22), focal nodular hyperplasia (n=1), and metastases (n=10). All images were graded in terms of lesion conspicuity, margin sharpness, and overall image quality using a 4- or 5-point
scale. In the cases of cystic lesions, posterior acoustic enhancement and internal artifacts were also analyzed. A Friedman
test was used for multiple statistical comparisons of the four techniques for all parameters. Compound imaging was significantly
superior to fundamental imaging regarding lesion conspicuity, margin sharpness, and overall quality (P<0.05). For posterior enhancement and internal artifacts within the cyst, harmonic ultrasonography (US) was significantly
better than fundamental US (P<0.05). For evaluating focal hepatic lesions on US, compound imaging provided better lesion conspicuity, better margin sharpness,
and better overall image quality than fundamental imaging did. Tissue harmonic imaging also provided better posterior enhancement
and fewer internal artifacts of the cyst than fundamental imaging. |
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Keywords: | Liver Neoplasm US Techniques |
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