得宝松局封联合咪喹莫特乳膏治疗瘢痕疙瘩疗效评价

目的:评价复方倍他米松注射液皮损内注射联合5%咪喹莫特乳膏外涂治疗瘢痕疙瘩的疗效。方法:将患者随机分为两组,治疗组给予复方倍他米松注射液皮损内注射,每3周1次,共3次。同时给予隔日外涂5%咪喹莫特乳膏,连续3个月;对照组单纯给予复方倍他米松注射液皮损内注射。两组患者均于疗程结束后6个月评价疗效和复发。结果:治疗组有效率93.55%,对照组有效率70.37%,复发率治疗组低于对照组,差异有显著性意义,不良反应轻微。结论:复方倍他米松注射液皮损内注射联合5%咪喹莫特乳膏外涂治疗瘢痕疙瘩安全、有效。

Assessment of compound betamethasone injection combined with topical imiquimod cream in the treatment of keloid

Objective： To assess the therapeutic efficacy of compound betamcthasone injection combined with local injection with 5% imiquimod cream in the treatment of kcioid. Methods： The patients were randomly divided into two groups. The treatment group was given intralesional compound betamethasone, once every 3 weeks for 3 times, combined with topical daily 5% imiquimod cream for 3 months. The control group only received compound betamethasone intralesional injection. The clinical efficacy and side effects were assessed after 6 months. Results： The effective rates in the treatment and control group were 93.55% and 70.37%, respectively, with a significant difference. The recurrence rate was lower in the treatment group than in the control group, with a significant difference. The side effects were mild. Conclusion： Compound betamethasone injection combined with 5% imiquimod cream is safe and effective in the treatment of keloid.