308nm准分子激光联合卡泊三醇软膏治疗斑块状银屑病疗效评价

目的：评价308 nm准分子激光联合卡泊三醇软膏治疗斑块状银屑病的临床疗效.方法：将93例稳定期斑块状银屑病随机分为3组,治疗组（33例） 予308 nm准分子激光照射,每周2次联合外搽卡泊三醇软膏,每日2次;对照1组（30例）外搽卡泊三醇软膏;对照2组（30例）,予308 nm准分子激光照射,方法同治疗组,2个月后判断疗效.结果：治疗组、对照1组和对照2组的有效率分别为90.91%、73.33%、63.33%.3组间疗效比较差异有统计学意义（均P〈0.05）.结论：308 nm准分子激光联合卡泊三醇软膏治疗斑块状银屑病能更好地提高疗效.

Assessment of efficacy of 308 nm excimer laser and calcipotriol ointment in the treatment of plaque psoriasis

Objective： To assess the efficacy of 308 nm excimer laser and calcipotriol ointment in the treatment of plaque psoriasis. Methods： Ninety-three patients with stable plaque psoriasis were randomly divided into three groups ： 33 patients were treated with twice-weekly 308 nm excimer laser in a combination of twice -daily calcipotriol ointment （group 1 ） ;30 patients were treated with twice-daily calcipotriol ointment （group 2） ; 30 patients were treated with twice-weekly 308 nm excimer laser （group 3） ; clinical assessment of the efficacy was made at the end of two months after the treatment. Results： The efficacy rates of the three groups were 90.91%, 73.33% and 63.33%, with a significant difference among the three groups （P〈 0.05）. Conclusion： 308 nm excimer laser in a combination with calcipotriol ointment is an effective alternative treatment for the patients with plaque psoriasis.