| 不同蛋白含量饮食对糖尿病大鼠肾组织核酸含量的影响 |
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| 引用本文： | 蒋更如 左静南. 不同蛋白含量饮食对糖尿病大鼠肾组织核酸含量的影响[J]. 上海交通大学学报(医学版), 1991, 11(2): 137-139 |
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| 作者姓名： | 蒋更如 左静南 |
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| 作者单位： | 上海第二医科大学附属新华医院内科(蒋更如，左静南，侯积寿，熊祖应，刘秀英)，上海第二医科大学附属新华医院内科(宋小君) |
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| 摘 要： | 将糖尿病鼠随机分成三组,分别饲以7%,20%和40%的蛋白质饮食一个月,结果发现7%组肾组织内核酸含量及RNA/DNA比率明显降低,而40%组则明显增加。提示蛋白质摄入量可以影响糖尿病大鼠肾组织内核酸的代谢,从而影响肾脏结构和功能。
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| 关 键 词： | 糖尿病 核酸 尿蛋白 肾 |
Effects of Dietary Protein Intake on Nucleic Acid Content of Kidney in Streptozotocin-Induced Diabetic Rats |
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| Jiang Gongru,et al. Effects of Dietary Protein Intake on Nucleic Acid Content of Kidney in Streptozotocin-Induced Diabetic Rats[J]. Journal of Shanghai Jiaotong University:Medical Science, 1991, 11(2): 137-139 |
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| Authors: | Jiang Gongru et al |
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| Affiliation: | Jiang Gongru,et al Department of Internal Medicine,Xinhua Hospital,Shanghai Second Medical University,Shanghai |
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| Abstract: | Streptozocin-induced diabetic rats were randomly divided into three groups and fed respectively with diets containing 7%, 20%, 40% protein. Decreased nucleic acid content and RNA/DNA ratio in the kidney were found in diabetic rats fed with low protein diet (7%) as compared with those normal protein (20%). In contrast, nucleic acid content and RNA/DNA ratio were increased in the group of animals fed with 400% protein diet. These results suggest that dietary protein intake may influence nucleic acid metabolism of the kidney in diabetic rats. |
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| Keywords: | animal experiment diabetes mellitus proteinuria kidney nucleic acid |
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