MR Imaging Findings of the Intraspinal Meningeal Melanocytoma: Correlation with Histopathologic Findings |
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Authors: | Hou G Q Sun J C Zhang X J Shen B X Zhu X J Liang L Zhang X L |
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Institution: | Department of Medical Image Center, Nanshan Hospital, Guangdong Medical College, Guangdong Province, People's Republic of China. |
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Abstract: | SUMMARY: Our aim was to better understand and improve the accuracy of the preoperative diagnosis of intraspinal MM by a combined analysis of MR imaging and pathologic findings. All 5 patients had undergone unenhanced and contrast-enhanced MR imaging examinations. All tumor samples had immunohistochemical reactions to HMB-45, vimentin, S-100, EMA, and Leu-7 antibodies. All 5 cases were located in the intradural extramedullary compartment. Two cases had multifocal lesions, and 3 cases were solitary. Two cases showed homogeneously strong enhancement, and 3 cases showed moderate enhancement on contrast-enhanced T1WI. The tumor cells had positive reactions to HMB-45, vimentin, and S-100 antibodies. MR imaging plays an important role in the detection and diagnosis of intraspinal MM. Final diagnosis should be based on histopathology and IHC examinations. |
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