| HPLC法测定益心颗粒中五味子醇甲的含量 |
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| 引用本文： | 王莉.HPLC法测定益心颗粒中五味子醇甲的含量[J].海峡药学,2013(12):101-102. |
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| 作者姓名： | 王莉 |
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| 作者单位： | 福建省三明市药品检验所,三明365000 |
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| 摘 要： | 目的 建立益心颗粒中五味子醇甲的含量.方法 采用高效液相色谱法.Welch Materials Cl8色谱柱（4.6mm×250mm,5μm）;流动相：甲醇-水（68：32）;检测波长：250nm;流速：1.0mL·min-1;柱温：25℃;进样量：10μL.结果 五味子醇甲在2.172μg·mL-1～34.752μg·mL-1范围内与其峰面积线性关系良好（r=0.9999）,平均回收率为98.93%,RSD为1.07%.结论 该方法快速、简便、结果可靠,可用于控制益心颗粒的质量.
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| 关 键 词： | 益心颗粒 五味子醇甲 HPLC 含量测定 |
Determination of schizandrin in Yixin Particles by HPLC |
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| WANG Li.Determination of schizandrin in Yixin Particles by HPLC[J].Strait Pharmaceutical Journal,2013(12):101-102. |
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| Authors: | WANG Li |
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| Institution: | WANG Li ( Fujian Sanming Institute for Drug Content, Sanming 365000, China) |
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| Abstract: | OBJECTIVE To establish a method for determination of schizandrin in Yixin Particles. METHODS The Welch Materials C18 column （4. 6mm × 250mm,5μm）was used. The mobile phase consisted of methanol-water （68：32） ;the flow rate was 1.0mL ·min- 1 ;the detection wavelength was 250nm;the column temperature was set at 25℃ ;the inject volume was 10μL. RESULTS A good linear correlation of Schizandrin was observed within the range of 2. 172μg· mL-1 - 34. 752μg · mL-1 （ r = 0. 9999 ）. The average recovery was 98.93% and RSD was 1.07%. CONCLUSION The method is rapid, simple and believable. It can be used to control the quality of Yixin Particles. |
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| Keywords: | Yixin Particles Schizandrin HPLC Determination |
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